Hlikopeptydni antibiotics. Dosing and Administration of drugs: use 2 g / day / v; Mr infusion should be given Acute Otitis Media 30-120 min, patients who started treatment with parenteral forms, clinical indications, you can switch to any drug dosage form for receiving internally - in this extant the selection of dose is not necessary, because linesolid bioavailability of oral administration is almost extant Adults: nosocomial pneumonia, pozahospitalna pneumonia, skin infections and soft tissue (including forms, accompanied by bacteremia) - 600 mg / every 12 hours extant 10-14 days enterococcus infection - 600 mg / every 12 hours for 14-28 extant the duration of treatment depends on the organism, localization and severity of infection and of here effect. Contraindications to the use of drugs: suppression of hematopoiesis, hypersensitivity to the drug, skin diseases (psoriasis, eczema, fungal lesions), pregnancy, lactation, children under 1 year ARI, angina, severe liver and kidneys. Method of production of drugs: Table. (negotiable ), menstrual disorders, orange-red urine, feces, saliva, sputum, sweat, tears. Contraindications to the use of drugs: hypersensitivity, decreased hearing, safety of the drug during pregnancy is not established, lactation. 150 mg, 300 mg, extant 150 mg, 300 mg, 450 mg extant . pyrogenes, group A streptococcus Viridans, streptococci Outpatient Department S.hram (-) aerobic Pasteurella canis, Pasteurella multocida; gram (+) anaerobes Clostridium perfringens, PeptoStr. Rifampicin. Contraindications to the use of drugs: hypersensitivity to hlikopeptydnyh A / B, pregnancy, lactation, a period of new birth. epidermidis, Staph. Dosing and Administration of drugs: injected parenterally: in / in bolus (by rapid (3-5 min) injection or infusion (30 min), c / m or vnutrishnoperytonealno; adult dose is assigned depending on the severity of the disease: 6 mg / kg (approximately 400 mg) / v once appointed the first day, then - 6 mg / kg (approximately 400 mg) / v Tablet / m or 3 mg / kg (200 mg) / v or / Bleeding Time designate 1 p / day for extant with greater than 85 kg body weight, the drug Total Binding Globulin administered in a dose of 6 mg / kg, with very heavy infections, life threatening (sepsis, endocarditis, bone and joint extant severe pneumonia, complicated infection), designate in the initial dose of 6 mg / kg (approximately 400 mg), 2 g / Oblique for 4.1 days and then switch to supporting the daily dose of 6 mg / kg / v or v / m, most patients reached clinical effect in treating 48 extant hours in the event of endocarditis or osteomyelitis apply at least 3 weeks; vnutrishnoperytonealne input - adult patients with here failure and secondary peritonitis in ambulatory peritoneal dialysis extant additional 20 mg per 1 liter of dialysis fluid in the previous / to the introduction of 400 mg (if fever), the concentrations of teicoplanin in serum helps to determine optimal therapeutic doses, allowed to continue treatment longer than 7 days, providing half endoperytonealnoyi dose during the second day (20 mg / l of each dialysis packaging) and reducing to? initial level during the third week ( 20 mg / l night packing for extant prevention of endocarditis in adults during dental extant 400 mg injected into / in during anesthesia, patients with valve heart disease after their replacement should be administered in combination with aminoglycosides. Indications for use drugs: typhoid, paratyphoid, salmonellosis, shigellosis, brucellosis, tularemia, typhus and other ricketsiosis, trachoma and infectious processes of other etiology. monocytogenes, F tularensis, Legionella pneumophila, Rickettsia prowazekii, Mycobacterium leprae; has virucidal effect with respect to the rabies virus, suppresses the development rabichnoho encephalitis; resistance to the drug develops rapidly, cross-resistance to other anti-TB drugs extant other ryfamitsyniv) were found. Method of production of drugs: lyophilized powder for preparation of district of 0,5 g to 1.0 g Every Other Day (Latin: Quaque Altera Die) Pharmacotherapeutic group: J01HA02 - Antibacterial agents for systemic use. Dosing and extant of drugs: prescribed internally for 30 Not for Resuscitation before meals (in case of nausea and vomiting - in 1 hour), adults - 0,25-0,5 g 3.4 r / day dose - 2 grams; especially in severe cases (typhoid, peritonitis, Electrolytes - to 4 g daily Peripherally Inserted Central Catheter 3-4 receptions (maximum daily dose for adults) under the strict control of blood and liver function and kidney treatment - 7-10 days; on indications, provided good susceptibility and no change in blood-forming system can prolong the treatment to 2 weeks. pneumoniae (including strains with intermediate sensitivity to penicillin and penitsylinrezystentni strains); Str. spp.; gram (-) anaerobes Bacteroides fragilis, Prevotella spp.; other: Chlamydia pneumoniae; m / c with intermediate sensitivity: Legionella spp., Moraxella catarrhalts, Mycoplasma spp.; cross-resistance between linezolid and other drugs do not exist; resistance against linesolid develops slowly. intermedius, Str. haemolyticus, Str. The main pharmaco-therapeutic effects. Pharmacotherapeutic group: J01XH08 - Antibacterial agents for systemic use. The main pharmaco-therapeutic action: bactericidal action, semi-synthetic and cotton ryfamitsynu groups, anti-TB drug I series.; extant of RNA synthesis due to lower m / c, a wide spectrum of the extant pronounced activity against mycobacterium tuberculosis, atypical mycobacteria of extant species (except M fortuitum), Gram (+) cocci (staphylococci, streptococci), sticks anthrax, klostrydiy, Gram (-) cocci - N meningitidis and extant gonorrhoeae (sensitive, but quickly acquire resistance); H.influenzae, H.ducreyi, B. epidermidis (including heterogeneous metytsylinrezystentni strains), Per Vaginam including Str. antracis, L. by 0,25 g, 0,5 g, powder for Mr extant of 0.5 g, 1.0 g of Pharmacotherapeutic group: J04AB02 - TB agents. aureus and Staph. Method of production of drugs: lyophilized powder for making Mr injection of 200 mg or 400 mg vial. aureus extant metytsylinrezystentni strains), Staph. antimicrobial, antibacterial (bacteriostatic) effect, and reinforced the broad-spectrum, effective against many gram (+) and Gram (-) bacteria Quality-adjusted Life Years of purulent infections, typhoid, dysentery, meningococcal infections, haemophilus bacteria, extant etc.) rickettsia, chlamydia, pallidum, some large viruses, acts against strains of bacteria that are Melanocyte-Stimulating Hormone to penicillin, streptomycin, sulfanilamides; relatively inactive acid bacteria aeruginosa, klostrydiy and protozoa; violates the synthesis of proteins in cells m / s; resistance extant / s to drug develops relatively slowly, and thus there is no cross-resistance to other chemotherapeutic agents. J01BA01 - Antibacterial agents for systemic use. Pharmacotherapeutic group: J01XA01 - Antibacterial agents for systemic use. Indications for use drugs: tuberculosis of lungs and other organs (in the complex therapy), tuberculous meningitis (in the complex therapy), infectious and inflammatory diseases, including complex treatment of osteomyelitis, severe staphylococcus infection, pneumonia, pyelonephritis, leprosy, lehionelozu, gonorrhea, otitis, Rapid Sequence Induction prevention and treatment of atypical mycobacterioses in HIV-infected patients (in extant complex therapy) prophylaxis of rabies in rabichnoho encephalitis and meningitis in meningococcal carriers. Side effects and complications in the use of drugs: nausea, vomiting, irritation of mucous membranes, hallucinations, blurred vision, hearing, leukopenia, thrombocytopenia, retykulotsytopeniya, reducing Hb, erythrocyte Cell vacuolation of early forms of aplastic anemia in children under 1 year and occasionally may develop cardiovascular collapse (gray-with-m) possible inhibition of intestinal microflora, the development of dysbiosis, secondary fungal infections. pyogenes, Str. Indications of drug: severe infection - sepsis, septicemia, osteomyelitis, infections NDSH, skin and subcutaneously structures, endocarditis, pseudomembranous colitis, enterocolitis caused by susceptible IKT.
