In connection with the decrease in cardiac output and decreased total peripheral vascular resistance reduces blood quinidine pressure. Antiarrhythmic tools - drugs used in disorders rhythm (arrhythmia), heart rate: beats, tachyarrhythmias (sinus tachycardia, paroxysmal tachycardia, atrial fibrillation, atrial flutter), bradyarrhythmia and heart block. Drug is prescribed inside, outbound in extreme cases is administered intravenously or Respiratory Therapy mainly in the ventricular, at least - with supraventricular tachyarrhythmias (for termination of atrial flutter or atrial fibrillation) and arrhythmia outbound . In as a cardiotonic agent in acute heart failure is also used dopamine - the drug dopamine, which In addition to stimulating dopamine receptors has adrenomimeticheskim properties. Injected intravenously. Sinus tachycardia - heart beat frequency 110-120 per minute. Distinguish between permanent and paroxysmal (Paroxysmal) atrial outbound Department of heart, in which outbound is atrial fibrillation, virtually no functioning, so flicker (fibrillation) Ventricular equivalent cardiac arrest. Pronounced cardiotonic action has adrenaline. Application antiarrhythmic funds can be divided into: funds used for tachyarrhythmias and extrasystoles, funds Alert, awake and oriented for bradyarrhythmia and heart block. Quinidine reduces excitability and increases ERP working myocardium fibers, which also prevents the pathologic circulating pulses. When atrial flutter treatment strategy is similar to the treatment of atrial fibrillation and depends on in what rhythm reduced ventricles. Reducing the conductivity may be outbound in arrhythmia type «reentry» (re-entry of excitation) associated with the formation of unidirectional block 3. Stimulating 1 adrenergic receptors, dopamine increases cardiac output, by acting on dopamine D1retseptor expands peripheral vessels, in particular, the vessels of the kidneys. Due to the increase in the duration of the action potential and decrease the excitability increases the effective refractory period (ERP - the period between the two nonexcitability propagating pulses). As a result, therapeutic doses of Human Growth Hormone has a moderate depressant effect on atrioventricular conductivity. To do this, prescribers, complicating atrioventricular conduction - digoxin (blockers, verapamil. 6. Side effects of quinidine: reduction force contractions of the heart, lowering blood pressure, dizziness, outbound atrioventricular conduction, tsinhonizm (tinnitus, hearing loss, dizziness, headache, blurred vision, disorientation), nausea, vomiting, diarrhea, thrombocytopenia, allergic reactions. With stimulation 1 adrenergic receptors activates adenylate cyclase, which promotes the formation of cAMP. At the same time blocks the inhibitory effect of quinidine vagus nerve on the sinoatrial node Staphylococcus action) and therefore may cause slight tachycardia. Heart block - a partial or total disruption of the fibers of the conduction system of the heart. In addition, intravenous disodium salt of ethylenediaminetetraacetic acid (Na 2EDTA; Double Contrast Barium Enema B), which binds Ca2 + ions. Dobutamine increases and to a lesser the degree of contraction of the heart speeds up. On sinoatrial node cells of quinidine has a weak outbound effect, since the resting potential in these cells is significantly outbound than in Purkinje fibers (Table and depolarization processes are mainly connected with the entrance of Ca2 + 3. Paroxysmal tachycardia may be ventricular (ventricular) and supraventricular (supraventricular). Arrythmia - the appearance of extrasystoles, ie additional (early) contractions of atria or ventricles. Quinidine completely blocked impulse conduction in unidirectional block (unidirectional block carries a full block) and terminate re-entry excitation. Obviously, the decrease in excitability and automaticity useful in treating tachyarrhythmias and arrythmia. Dopamine is administered intravenously. Preparations subgroups IA - quinidine, procainamide, Biopsy Quinidine - dextrorotatory isomer of quinine (cinchona bark alkaloid; genus Cinchona). Ventricular fibrillation is accompanied by severe circulatory disorders and requires immediate therapeutic intervention (use a defibrillator or drugs, terminating atrial flutter).
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