Duration of action 12-24 hours Ethacrynic acid (Uregei) similar to that of furosemide on the action and efficiency. Due to the increase of osmotic pressure by the action of mannitol are diagnostician increase the volume of blood plasma and the load on the heart (not recommended for heart failure). Because of violations of water reabsorption occurs dilution of leachate, diagnostician the concentration of the filtrate of Normal +, CI and therefore violated their reabsorption. diagnostician limits use of mannitol, as many of poisoning accompanied by heart failure. Mannitol - a strong akvaretik and weak natriyuretik. Spironolactone - diuretic reasonable efficiency. So as mannitol in the renal tubules is not reabsorbed in the tubules increases, the osmotic pressure of the Xia. The value of diuretic effect is increased with increasing levels aldosterone. More active (assigned in smaller doses). Produces nearly 20% Na + filtrate. Excretion here uric acid diagnostician Reduced reabsorption of ions in the thick segment of loop of Henle decreases osmotic-static pressure in the interstitial fluid surrounding tissue. To a greater degree of violation hearing, an irritant, the following properties. It also provides a high diuretic effectiveness of loop diuretics. Not metabolized in the body by filtering and released in the renal tubules. In the liver of cholesterol, bile acids are formed. When administered after approximately 30 min in TE chenie 4-6 hours when administered intravenously action starts in 10 minutes and lasts 2-3 hours Side effects of furosemide: frequent urination, weakness, head-spinning, dry mouth, nausea, hypokalemia (Less than with thiazides), hypomagnesemia, hypocalcemia, hyper-perkaltsiuriya (contraindicated in urolithiasis) hyperuricemia, hyperglycemia, hearing loss (changes the ionic composition of endo-lymph), paresthesia, photosensitivity of skin, skin rash. Assign hypertension inside the 1 time a day "Loop diuretics" more effective than thiazides and tiazidopodob-nye connection. Thus, mannitol primary violates the reabsorption of water and again - the reabsorption of Na + and C1. Bendroflumetiazid more efficiently tsiklometiazida; operates 12 hours Metiklotiazid operates 24 hours Klopamid (brinaldiks) and metolazone are 12-24 h, chlorthalidone (oksodo-ling, gigroton) - up to 3 days. In the wall of the intestine dietary cholesterol-rin, and triglycerides are involved in the formation of XM, who through the lymphatic diagnostician enter the bloodstream. In the fatty tissue under diagnostician influence of endothelial lipoprotein diagnostician XM vessels and their constituent triglycerides are split, released fatty acids penetrate Human Leukocyte Antigen the fat cells and participate in the formation of triglycerides diagnostician . Amiloride and triamterene - weak diuretics; appointed interior, amiloride and Acts 24 hours, 12 hours triamterene Applied combination with a diuretic, which contribute to the removal of K + and Mg2 + from the body (thiazides tiazidopodobnye diuretics, loop diuretics). Mannitol - a compound which almost does not penetrate the biological membrane. Injected intravenously in the form of infusion of 10-20% diagnostician Increases the osmotic pressure of blood plasma in connection with what occurs dehydration of brain tissue, eyes (no mannitol penetrates the blood-brain and blood aqueous barrier). Only if enough Cholesterol synthesis of LDL receptors is terminated. Indapamide (Arifon) is different from diagnostician diuretics that, in addition to diure, kinetic action, directly extends blood vessels and reduces total peripheral vascular resistance and blood pressure.
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